O QUE FOI APRESENTADO
Finalidade da operação
The present proposal establishes groundbreaking hypotheses and innovative ideas that will ultimately contribute to addressing the challenges associated with the increasing aging of the global population. The PREDICT2TREAT aims to obtain several insights, both of the host and the respective commensal microbial populations, which could be used to improve routine clinical practice. In line with this, the following objectives are planned: 1) Profiling of the genetic variants of genes encoding for purinergic receptors, which are known as being involved in the modulation of inflammatory responses and responsible for the control of damages, in two age groups, elderly (>65 years old) and young adults (18-40 years old); 2) Identification of the microbiota and mycobiota associated with the selected…
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The present proposal establishes groundbreaking hypotheses and innovative ideas that will ultimately contribute to addressing the challenges associated with the increasing aging of the global population. The PREDICT2TREAT aims to obtain several insights, both of the host and the respective commensal microbial populations, which could be used to improve routine clinical practice. In line with this, the following objectives are planned: 1) Profiling of the genetic variants of genes encoding for purinergic receptors, which are known as being involved in the modulation of inflammatory responses and responsible for the control of damages, in two age groups, elderly (>65 years old) and young adults (18-40 years old); 2) Identification of the microbiota and mycobiota associated with the selected elderly vs young adults’ groups of individuals, to identify major groups, genera or species, relevant to wellbeing and healthy ageing; 3) To study phenotypes and genotypes of C. albicans strains isolated as gut colonizers in the studied population, to construct a scale of virulence, highlighting strains that may be contributing to health and that can be used as new probiotics; 4) To establish a correlation model using the data collected throughout the study, with the main and final goal of calculating a risk score to be used in Precision Medicine to, ultimately, increase the elderly healthspan and wellbeing.
PROGRAMA E OBJETIVOS
Como a operação está enquadrada
- Programa
- Programa Inovação e Transição Digital
- Fundo
- Fundo Europeu de Desenvolvimento Regional
- Objetivo estratégico
- + Inteligente
- Objetivo específico
- Reforçar a investigação, inovação e adoção de tecnologias avançadas.
- Área temática
- Investigação, Desenvolvimento e Inovação
- Atividade económica
- Atividades de investigação
- Modalidade
- Subvenção
- Taxa de cofinanciamento
- 85%
ONDE
Distribuição territorial publicada
Localização observada no ficheiro de 31 de agosto de 2026.
QUANDO
Calendário publicado
- Início previsto
- 3 de novembro de 2025
- Início efetivo
- 18 de junho de 2026
- Conclusão prevista
- 1 de novembro de 2028
- Conclusão efetiva
- Não indicada